Compatible Stability of Fructose Injection with 5 Kinds of Drugs
- VernacularTitle:果糖注射液与5种药物的配伍稳定性考察
- Author:
Meifang JIANG
;
Xianmin LI
- Publication Type:Journal Article
- Keywords:
Fructose injection;
Compatible;
Stability
- From:
China Pharmacy
2005;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine compatible stability of Fructose injection mixed with 5 kinds of drugs respectively,i.e. cefradine for injection,ribavirin injection,aciclovir for injection and levofloxacin hydrochloride for injection,penicillin for injection. METHODS:UV spectrophotometry was applied to investigate appearance,pH value,content and insoluble particle of mixtures. RESULTS:There was no significant change in respect of appearance,pH value and content after Fructose injection mixed with cefradine for injection,ribavirin injection,aciclovir for injection,penicillin for injection respectively. Results of study showed good compatible stability of mixtures. The content and pH value were decreased after Fructose injection mixed with levofloxacin hydrochloride for injection and precipitation was found in mixture. CONCLUSION:Fructose injection mixed with cefradine for injection,ribavirin injection,aciclovir for injection,penicillin for injection are stable and reliable. It should be careful to apply the mixture of Fructose injection with levofloxacin hydrochloride for injection.
