Application of Non-parametric Bootstrap Method in the Evaluation of Confidence Intervals of Cost-effectiveness
- VernacularTitle:非参数Bootstrap法在成本-效果置信区间估计中的应用
- Author:
Ying XIE
;
Xin ZONG
;
Lihua SUN
- Publication Type:Journal Article
- Keywords:
Non-parametric Bootstrap method;
Confidence intervals;
Cost-effectiveness ratio
- From:
China Pharmacy
2005;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide a simple and reliable method to estimate confidence intervals of incremental cost-effectiveness ratios for pharmacoeconomics evaluation in China. METHODS:Through retrieving relevant foreign literature,the idea and mathematical properties of non-parametric Bootstrap method were described and the method for calculating confidence intervals were explained by giving an example. RESULTS&CONCLUSION:Non-parametric Bootstrap method is simple and reliable for the calculation of confidence intervals of pharmacoeconomics. When the distribution of samples is skewed significantly or the sample size is not plenty enough,we still need to be cautious to adopt non-parametric Bootstrap method.
