Clinical Efficacy of the Self-made TCM on Toxicity of PR Combined with CTX Treatment for Lupus Nephritis
- VernacularTitle:中药自拟方对PR与CTX联合治疗狼疮肾炎的解毒作用及临床观察
- Author:
Hongli YAN
;
Yaling LI
- Publication Type:Journal Article
- Keywords:
Lupus nephritis;
Metacortandracin;
Cyclophosphamide;
Self-made TCM prescription
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore optimal regime and less ADR for lupus nephritis(LN) by adopting self-made TCM prescription.METHODS:109 LN patients were assigned into control group(n=48) and therapy group(n=61).Both groups were treated with metacortandracin and cyclophosphamide.Control group were additionally given self-made TCM prescription.The clinical efficacy and adverse drug reaction(ADR) of 2 groups were compared.RESULTS:The curative rate and total response rate of therapy group were 77.05%(47/61) and 95.08%(58/61) respectively and those of control group 58.33%(28/48) and 77.08%(37/48).The curative rate and total response rate of therapy group were all higher than those of control group.There were significant difference between 2 groups(P
