Meta-analysis of Domestic Sparfloxacin for Acute Bacterial Infections with Oral Administration
- VernacularTitle:国产司帕沙星治疗急性细菌感染的Meta分析
- Author:
Chuanxin XU
;
Zongxi WANG
;
Yan HU
;
Xianling SHEN
;
Feng XIAO
- Publication Type:Journal Article
- Keywords:
Sparfloxacin;
Acute bacterial infections;
Randomized controlled trials;
Meta-analysis
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To assess the clinical efficacy and safety of domestic sparfloxacin for acute bacterial infections.METHODS:Domestic literatures about sparfloxacin for acute bacterial infections were retrieved by computer and their quality was evaluated to extract data(1993～2009).RevMan 4.2.2 software was used for Meta-analysis.RESULTS:A total of 10 RCT were enrolled.The comparisons of 2 groups were homogeneous in terms of clinical cure rate,clinical response rate,bacterial clearance rate and safety.There was statistical significance in comparison of combined effect variable between 2 groups in respect of cure rate,response rate and bacterial clearance rate(P0.05).CONCLUSION:The currently available evidence shows that clinical efficacy of domestic sparfloxacin for acute bacterial infections is better and incidence of ADR was lower.
