Clinical Efficacy of Levoearnitine Combined with Trimetazidine in the Treatment of Ischemic Cardiomyopathy Heart Failure in Elderly
- VernacularTitle:左卡尼汀联合曲美他嗪治疗老年缺血性心肌病心力衰竭的疗效观察
- Author:
Miao ZHONG
;
Tingting LI
;
Ruofei SHI
- Publication Type:Journal Article
- Keywords:
Levoearnitine;
Trimetazidine;
Ischemic cardiomyopathy;
Heart failure;
Efficacy
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore clinical efficacy of levoearnitine combined with trimetazidine in the treatment of ischemic cardiomyopathy(ICM) heart failure in elderly patients.METHODS:64 ICM elderly patients with heart failure were randomly divided into control group and observation group(n=32).Both group were given therapy of regulating blood lipid,antiplatelet,anti ischemia and conventional anti-heart failure therapy.Observation group were additionally intravenously injected with levoearnitine and given oral dose of trimetazidine for 2 weeks.Cardiac function classification,left ventricular end-diastolic diameter(LVEDD),left ventricular end systolic diameter(LVESD) and left ventricular ejection fraction(LVEF) of patients were determined before and after treatment.RESULTS:The cardiac function and the level of LVEDD,LVESD and LVEF in observation group were all significantly better than in control group.There were statistical significance in difference between two groups(P
