Other Effects of Cimetidine in the Decompensated Stage of Chronic Cardiopulmonary Disease
- VernacularTitle:西咪替丁治疗慢性肺心病上消化道出血以外的效应
- Author:
Jianchang YU
;
Yufang ZHANG
;
Yuxin WANG
- Publication Type:Journal Article
- Keywords:
Cimetidine;
Chronic cardiopulmonary disease;
Decompensated stage;
Gastrointestinal bleeding
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the other effects of cimetidine in the decompensated stage of chronic cardiopulmonary disease. METHODS: 72 patients with uncompensated chronic cardiopulmonary disease were assigned into therapy group and control group (n=36). Both groups were given routine treatment. Therapy group were additionally treated with cimetidine intravenously for 48 h. The changes of respiration frequency, arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), intake of staple food and electrolytes in blood serum of 2 groups before and after treatment were determined. RESULTS:In therapy group, the respiration frequency, the level of PaCO2 and disorder of electrolytes in blood serum were decreased and the level of PaO2 and intake of staple food were increased. Above items of therapy group were all different from that of control group (P
