Literature Analysis of 2 Cases of Cross Allergic Reaction between Carbopenem and Penicillin
- VernacularTitle:碳青霉烯类与青霉素交叉过敏2例并文献分析
- Author:
Jing LAI
;
Weiqiang GAN
;
Lifen HUANG
;
Youming CHEN
- Publication Type:Journal Article
- Keywords:
Carbapenems;
Penicillin;
Cross allergic reaction;
Cases report;
Literature
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the characteristics and regularity of cross allergic reaction between carbopenems and penicillin.METHODS:2 cases about cross allergic reaction between ertapenem and penicillin were reported,716 cases of cross allergic reaction between carbopenems and penicillin in 9 literatures were collected from databases from Jan.1986 to Jan.2010 and analyzed statistically.RESULTS:The incidence of allergic reactions caused by carbopenems in patients with allergic history were higher than that in patients without allergic history.Allergic reaction mostly occurred within 15 min～49 d.Sound therapeutic efficacy can be achieved because of immediate withdrawal of drug and anti-allergy treatment,patients were with good prognosis.CONCLUSION:Great importance should be attached to monitoring of cross allergic reaction between carbopenems and penicillin and rational use of drugs.
