Progress of mechanism and related treatment of acute pancreatitis
- VernacularTitle:急性胰腺炎发病机制及相关治疗的研究进展
- Author:
Xuhong LIN
;
Yongyu LI
- Publication Type:Journal Article
- Keywords:
Acute pancreatitis;
Mechanism;
Treatment
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Although we have understood only limited knowledge about the pathophysiological mechanisms of acute pancreatitis (AP),it has at least been proven that the activation of pancreatic zymogens inside the pancreatic acinar cells,as well as the inflammatory reaction resulting from the inflammatory mediators,including the cytokines and oxygen free radicals,constitute the main reason for the early pathological processes of AP. The inflammatory mediators also facilitate the complications such as lung injury and multiple organ dysfunctions. The bacterial translocation,which aggravates the pathological changes and increases the mortality in AP,causes the pathophysiological vicious circle in the later period of the disease. There is no doubt that the levels of the clinical prevention,diagnosis and treatment for AP will be greatly improved along with the elucidation of its pathogenesis.
