ExpExperimental study on sentinel lymph node biopsy of breast cancer by carbon nanoparticles suspension injection
- VernacularTitle:纳米炭在乳腺癌前哨淋巴结示踪的实验研究
- Author:
Huan QU
;
Yanan ZHANG
;
Weidong CHEN
- Publication Type:Journal Article
- Keywords:
Breast Neoplasms;
Carbon Nanoparticles;
Sentinel Lymph Node;
Disease Model,Animal
- From:
Chinese Journal of General Surgery
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy of carbon nanoparticles suspension and methylene blue for the detection of axillary sentinel lymph nodes in rabbits with breast cancer,to provide a method for the clinical application of treatment of breast cancer.Methods The model of breast cancer was established in 40 rabbits by intramammary injection of VX2 tumor tissue suspension 1ml.The successful model was divided into two groups.Carbon nanoparticles suspension and methylene blue were used in staining sentinel lymph node.The staining time,stain fading time of SLN,number of stained SLN,total number of the stained lymph node and the staining effect were observed.Results The staining time of SLN and number of stained SLN had no significant difference between the 2 groups,total number of the stained lymph nodes was 3.25?0.56 and 2.3?0.21 respectively in carbon nanoparticles suspension group and methylene blue group(t=6.99,P
