Analysis on efficacy of zoledronic acid combined with taxotere in treatment of breast cancer with bone metastases
- VernacularTitle:唑来膦酸联合泰索帝治疗乳腺癌骨转移效果观察
- Author:
Zhiheng HUANG
;
Xiaming WANG
- Publication Type:Journal Article
- Keywords:
Breast Neoplasms;
Bone Metastases;
Zoledronic Acid;
Taxotere
- From:
Chinese Journal of General Surgery
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and safety of zoledronic acid combined with taxotere in treatment of breast cancer patients with multiple bone metastases and negative hormone receptors.Methods Thirty-six breast cancer patients with multiple bone metastases were randomized devided into two groups: Group A(zoledronic acid plus taxotere) and Group B(zoledronic acid alone).The effect in the two groups was compared.Results Relief of bone pain,improvement in quality of life,and toxic side effects between the two groups showed no significant difference.The effect on bone metastases was 66.7%(12/18)in group A,which was significantly higher than that in group B(11.1%,2/18)(P
