Clinical Observation of Polyene Phosphatidyl Choline Combined with Atorvastatin for Alcoholic Liver Disease
- VernacularTitle:多烯磷脂酰胆碱联合阿托伐他汀治疗酒精性肝病的临床观察
- Author:
Yuhong LIU
;
Hongliang CAI
;
Liya MU
- Publication Type:Journal Article
- Keywords:
Polyene phosphatidyl choline;
Atorvastatin;
Alcoholic liver disease
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the therapeutic efficacy and safety of polyene phosphatidyl choline and atorvastatin in the treatment of alcoholic liver disease. METHODS:112 patients with alcoholic liver disease were randomly divided into control group (n=56)and treatment group(n=56). Both groups were given a cure for alcoholism,vitamin and polyene phosphatidyl choline (465mg,qd,i.v. gtt)therapy. Treatment group were additionally treated with torvastatin(10 mg,po)once a day before bed for 4 weeks. Clinical symptoms,signs,liver function,blood lipid changes of two groups before and after treatment were observed. RESULTS:Treatment group was superior to control group in respect of clinical symptoms,signs,liver function and blood lipid changes(P
