Efficacy of Cefazolin vs. Cefuroxime in Preventioning Cesarean Section Wound Infection
- VernacularTitle:头孢唑啉与头孢呋辛预防剖宫产术切口感染的疗效比较
- Author:
Lingao YI
;
Xiaochan XIANG
;
Jie LIN
- Publication Type:Journal Article
- Keywords:
Cefazolin;
Cefuroxime;
Cesarean section;
Wound infections;
Antibiotics to prevent
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the efficacy of cefazolin and cefuroxime prevention of perioperative cesarean section wound infection. METHODS:291 cases of elective cesarean section surgery,according to the use of medicines are divided into group A(n=140)and group B(n=151),were retrospectively analyzed. Patients in group A,preoperative 30 min intravenous infusion of cefazolin 2.0 g;after surgery,2.0 g ivgtt,q12 h,continue to use 2～5 days. Patients in group B,preoperative 30 min intravenous infusion of cefuroxime 2.0 g;after surgery,2.0 g ivgtt,q12 h,continue to use 2～5 days. Comparison of the clinical effect of 2 groups patients. RESULTS:WBC,N%,Hb,complications,body temperature,wound healing had no statistical difference in postoperative between 2 groups. All patients were not the emergence of drug adverse reactions. CONCLUSION:cefazolin and cefuroxime has the same efficacy of prevention of cesarean section wound infection.
