Effect of Bushen Tiaojing Decoction on Serum Leptin, Insulin and Tes tosterone of Polycystic Ovary Syndrome Model Rats
- VernacularTitle:补肾调经汤对多囊卵巢综合征模型大鼠血清瘦素、胰岛素和睾酮的影响
- Author:
Guangrong FENG
;
Xiaohua HU
;
Yanyan ZHOU
- Publication Type:Journal Article
- Keywords:
Polycystic ovary syndrome (PCOS);
Bushen Tiaojing D ecoction (Decoction for reinforcing the kidney and regulating the menstruation);
Leptin;
Insulin;
Testosterone;
Rat
- From:
Journal of Traditional Chinese Medicine
1993;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect and mechanism of Bush en Tiaojing Decoction (Decocti on for reinforcing the kidney and regulating the menstruation) on ovulation of p olycystic ovary syndrome (PCOS) rats. Methods Eighty fe male SD rats were made PCOS models and randomized into blank group, model group, metformin group, Bushen Tiaojing Decoction high and low dose group s, with 10 ones in each and the remainders removed. The changes of serum leptin, ins ulin and testosterone in each group were observed. Results In Bushen Tiaoji ng Decoction high and low dose groups, serum leptin, insulin and testosteron e were all decreased. The effect of Bushen Tiaojing Decoction high dose group wa s similar with that of metformin group in decreasing leptin, insulin a nd testosterone. Conclusion Bushen Tiaojing Decoction c ould improve the ovulation of PCOS rats through regulating leptin, insulin , and testosterone.
