Clinical significance of quantitative analysis of EBV DNA,CYFRA21-1 and VCA-IgA in nasopharyngeal carcinoma patients
- VernacularTitle:血浆EBV DNA、血清CYFRA21-1和VCA-IgA的检测在监测鼻咽癌患者复发和转移中的临床价值
- Author:
Jianguang SUN
;
Huaxiu WANG
;
Fanggeng XIAO
;
Yalin LIU
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal Neoplasms;
Herpes Virus4,Human;
DNA,Viral;
Keratin-19;
Prognosis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the clinical significance of quantitative analysis of EBV DNA in plasma,CYFRA21-1 and VCA-IgA in serum of nasopharyngeal carcinoma patients.METHODS EBV DNA in plasma,CRFRA21-1 and VCA-IgA in serum of 62 patients were analyzed using RealTime PCR technique,electrochemiluminescence immunoassay(ECI),and immunoenzyme assay respectively.And these were compared among clinical remission,recurrent or metastasis groups.RESULTS The positive rate of preoperative radiotherapy group was significantly higher than clinical remission group(P