Effect and Safety of Nabumetone in the Treatment of Rheumatoid Arthritis:A Meta-analysis
- VernacularTitle:国内萘丁美酮治疗类风湿关节炎的疗效及安全性的Meta分析
- Author:
Li LIU
;
Jing SU
;
Zhong YU
;
Tingting XU
- Publication Type:Journal Article
- Keywords:
Nabumetone;
Rheumatoid arthritis;
Curative effect;
Safety;
Meta-analysis
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To evaluate the clinical curative effect and safety of nabumetone for rheumatoid arthritis. METHODS: The researches about the study on the curative effect and ADRs of nabumetone for rheumatoid arthritis were retrieved and carried out by Meta-analysis. RESULTS: 9 researches were up to the including criteria. As compared with the control group, nabumetone has better effect [RR=1.11,95% CI(1.02, 1.20), P=0.01] but fewer ADRs [RR=0.71,95% CI(0.41, 1.22), P=0.007] in clinical treatment of rheumatoid arthritis. CONCLUSION: The evidence currently available shows that nabumetone has better efficacy and safety. Because the RCTs available for this systematic review are too small, more and further high-quality large-scale RCTs with long-term follow up are required to provide more reliable evidence
