Systematic Review of Diammonium Glycyrrhizinate in the Treatment of Drug-induced Liver Injury
- VernacularTitle:甘草酸二铵治疗药物性肝损害的系统评价
- Author:
Quanzhi LI
;
Jingli DUAN
- Publication Type:Journal Article
- Keywords:
Drug-induced liver injury;
Diammonium glycyrrhizinate;
Systematic review
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To evaluate the efficacy and safety of diammonium glycyrrhizinate in the treatment of drug-induced liver injury according to present clinical studies. METHODS: Retrieved from CBM and the CNKI from 1994 to 2009, literatures about the randomized controlled trials that the effective rate of diammonium glycyrrhizinate was compared with that of other hepatoprotective with drug-induced liver injury and drug-induced liver disease as study subjects. RESULTS: 18 RCTs including 1,644 patients with drug-induced liver injury were enrolled. The effective rate of diammonium glycyrrhizinate group was higher than that of control group, statistical significance was noted in two groups (P
