Analysis on the Characteristics of Early Adverse Drug Reaction of ~(131)I in the Treatment of Hyperthyroidism
- VernacularTitle:~(131)I治疗甲状腺功能亢进后早期不良反应的特点和分析
- Author:
Jianfeng LIU
;
Min XIE
;
Dan ZHENG
;
Chunbin GUO
;
Ran LIU
;
Jingjin WANG
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism;
131I;
Early adverse drug reaction
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate and analyze the characteristics of early adverse drug reaction (ADR) of 131I in the treatment of hyperthyroidism. METHODS: 468 hyperthyroidism patients treated with 131I were followed up for 1 year. RESULTS: After 2～7 days of treatment, different reactions occurred in 54 cases (11.50%) including rash, itch of skin and alopecia of 16 cases (3.40%), paroxysmal muscle spasm of 19 cases (4.10%), eye discomfort of 13 cases (2.80%), aggravated symptom of 3 cases (0.60%) and thyroid pain of 3 cases (0.60%). These ADRs can last about 2 weeks to one year, and then relieved themselves. CONCLUSION: 11.50% of hyperthyroidism patients treated with 131I complain early systemic or local adverse reactions which are relieved within several months.
