Clinical Observation on Treatment of Malignant Hydrothorax with Locally Administered Highly Agglutinative Staphylococcin and Cisplatin
- VernacularTitle:高聚金葡素联合顺铂局部治疗肺癌恶性胸腔积液的疗效观察
- Author:
Jian CHENG
;
Yuzhi AN
;
Xin ZHANG
;
Yadi WANG
;
Wei LIU
;
Yue WANG
;
Minwen HA
- Publication Type:Journal Article
- Keywords:
Hydrothorax;
Cisplatin;
Highly agglutinative staphylococcin
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To observe the clinical efficacy of highly agglutinative staphylococcin (HAS) combined with cisplatin in the treatment of malignant hydrothorax after straining and inserting central venous catheter in thoracic cavity. METHODS: 90 patients with malignant hydrothorax combined with lung cancer were randomly divided into A、B、C 3 groups. Central venous catheter was inserted in thoracic cavity for strainage. Group A were intrapleural injected with 5 000 U HAS, group B 40 mg?m-2 cisplatin and group C 5 000 U HAS combined with 40 mg?m-2 cisplatin once a week. Clinical efficacies of 3 groups were evaluated after 3 weeks of treatment. RESULTS: The total effective rate of group A, B and C were 43.0%, 46.7% and 80.0% respectively. There was obvious difference between group C and A as well as group B(P
