The effect of Qing Yi Tang on bacterial and endotoxin translocation from intestine in acute hemorrhagic necrotizing pancreatitis in rats
- VernacularTitle:清胰汤对急性出血坏死性胰腺炎肠道细菌及内毒素移位的影响
- Author:
Xiangying WANG
;
Xingwen ZHANG
;
Yan XIAO
;
Xiang LI
;
Yizhan LU
- Publication Type:Journal Article
- Keywords:
Pancreatitis,Acute Necrotizing /ther;
Qing Yi Tang;
Bacterial Translocation;
Rats
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Qing Yi Tang(QYT) on bacterial and endotoxin translocation from intestine in acute hemorrhagic necrotizing pancreatitis(AHNP) in rats.Methods SD rats were randomly divided into 3 groups: AHNP group,AHNP +QYT treatment group and sham operation(SO) group.AHNP models were set up in the former two group,while the pancreas was only mobilized in SO group.After setting up the model,QYT was gavaged in the QYT group,while normal saline was gavaged in the SO group and AHNP group.The concentration of endotoxin(ET) and the DNA of E.coli expressoin in portal vein blood in three groups of rats were measured 24h later.Results The concentration of ET and amount of E.coli DNA in portal vein of QYT group were lower than those of AHNP group.Conclusions QYT can reduce significantly the concentration of ET and E.coli DNA in portal vein blood and decrease bacterial and endotoxin translocation from intestine in the AHNP rats.
