Impacts and Safety Evaluation of Aldactone on Six-minute Walk Test Performance in Patients with High Altitude Heart Disease and Heart Failure
- VernacularTitle:螺内酯对高原性心脏病伴心力衰竭患者6min步行试验的影响及安全性评价
- Author:
Jianguo SHI
- Publication Type:Journal Article
- Keywords:
Aldactone;
High altitude heart disease;
Heart failure;
Six-minute walk test
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the impacts and safety evaluation of aldactone on six-minute walk test performance in patients with high altitude heart disease and heart failure.METHODS:41 inpatients with high altitude heart disease from Feb.2004 to Jun.2009 were randomly divided into treatment group (n=21) and control group (n=20).Both groups were given captopril,furosemide and digoxin,etc.for three months.Treatment group were additionally treated with aldactone (40～60 mg?d-1).RESULTS:The six-minute walking distances were increased in two groups after the treatment (P0.05).CONCLUSION:Aldactone shows sound effect on improvement of heart functions in patients with high altitude heart disease,at the same time it can improve motor functions and life quality of patients.So it is safe to administer aldactone in a short period.
