Influence of Different Combination of Yupingfeng Decoction on the Content of Calycosin-7-O-?-D-glucoside, Prim-o-glucosyl Cimifugin and 4′-O-?-D-glucosyl-5-O-methylvisammin
- VernacularTitle:玉屏风煎剂不同配伍对毛蕊异黄酮苷、升麻素苷、5-O-甲基维斯阿米醇苷含量的影响
- Author:
Yuechun HUANG
;
Gang WEI
- Publication Type:Journal Article
- Keywords:
Yupingfeng decoction;
Compatibility;
Calycosin-7-O-?-D-glucoside;
Prim-o-glucosyl cimifugin;
4′-O-?-D- glucosyl-5-O-methylvisammin;
HPLC;
Content
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a method for the content determination of calycosin-7-O-?-D-glucoside,prim-o-glucosyl cimifugin and 4′ -O-?-D-glucosyl-5-O-methylvisammin in Yupingfeng decoction and to study the influence of different combination on the content of three compositions.METHODS:HPLC was applied and the determination was performed on Hypersil ODS(250 mm?4.0 mm,5 ?m)column.The mobile phase consisted of acetonitrile-water(gradient elution)with detection wavelength of 254 nm.RESULTS: The content of the three compositions represented little change or different deceasing tendency in the decoctions of various compatibilities.The biggest deceasing tendency of content was found in the decoctions containing Astragalus membranaceus,Saposhnikovia divaricata,and Atractylodes macrocephala.CONCLUSIONS: The content of the three compositions of different combination shows a dynamic course,which provides a reference for the rules of the compatibility and material basis of Yupingfeng decoction.