Optimization of the Prescription of Traditional Chinese Medicine for MS by Uniform Design
- VernacularTitle:均匀设计法优化抗晕动中药处方
- Author:
Yan CHEN
;
Jingfeng XU
;
Jinping WANG
;
Ming ZENG
;
Weijuan ZHAO
- Publication Type:Journal Article
- Keywords:
Rhizoma zingiberis;
Herba pogostemonis;
Aucklandia lappa;
Motion sickness;
MS index;
Uniform design;
Prescription of traditional Chinese medicine
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the prescription of traditional Chinese medicine for motion sickness (MS).METHODS: Zingiber officinale,Herba pogostemonis,Aucklandia lappa were extracted respectively,and rotating-inducing MS mice were enrolled in uniform design.The prescription was optimized with MS index as the parameters.RESULTS: The optimal prescription was as follows:60 g Z.officinale,45 g Herba pogostemonis,5 g A.lappa.The extractive of prescription was significantly better than dimenhydrinate in the treatment of MS.CONCLUSION: MS index is a stable and sensitive parameters and it is suitable for screening and evaluation of anti-MS drugs.R.zingiberis,H.pogostemonis,A.lappq are potential drug for MS.
