Technology for Optimizing Extraction Method and Uniform Design of Anthraquinones Components of Radix et Rhizoma Rhei
- VernacularTitle:大黄蒽醌类成分的提取方法筛选及均匀设计优化工艺研究
- Author:
Honghua CUI
;
Shumei WANG
- Publication Type:Journal Article
- Keywords:
Radix et Rhizoma Rhei;
Anthraquinones components;
Heating reflux extraction;
Uniform design
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study extraction method of anthraquinones components of Radix et Rhizoma Rhei and optimize extraction technology.METHODS: Ultrasonic extraction,heating reflux extraction and soxhlet extraction were adopted to extract Radix et Rhizoma Rhei respectively.3 kinds of extraction technology were compared with the content of total anthraquinone,aloe-emodin,rhein,emodin,chrysophanol,physcione as index.The extraction technologies of UV and 5 kinds of anthraquinone compounds were optimized by uniform design method on the basis of previous study.RESULTS: Heating reflux extraction which was optimal extraction technology was as follows: extracting time of 90 min,extracting for 1 time,methanol concentrations of 95%,medicinal mesh of 2.000 7.Comprehensive score of anthraquinones could reach 6.556.CONCLUSION: The extraction technology is reasonable,available in quality control.
