Study of peritoneal cytokine measurement for early prediction of biliary fistula after biliary operations
- VernacularTitle:胆道术后腹腔引流液中炎性因子检测对胆瘘早期诊断的研究
- Author:
Bei ZHANG
;
Xiao LIU
;
Huantao HUANG
;
Zhigang WANG
- Publication Type:Journal Article
- Keywords:
Biliary Tract Surgical Procedures;
Biliary Fistula;
IL-6;
IL-8;
IL-10;
TNF-?;
C-Reactive Protein
- From:
Chinese Journal of General Surgery
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic and predictive value of measuring peritoneal inflammatory cytokines in predicting biliary fistulas in patients undergoing biliary surgery.Methods Peritoneal samples and serum samples of 3227 biliary surgery patients were collected on the first,third,fifth postoperative day,and IL-6,IL-8,IL-10,TNF-? and CRP of the samples were measured.Patients were divided into two groups:those with clinical evidence of biliary fistulas and those without any evidence of biliary fistulas.The age,sex,operative method and operative time between the two groups were compared.Results There was a negative correlation between biliary fistulas and age,sex and operation mode;but blood loss,operation time and common bile duct diameter had positive correlation with biliary fistulas.Peritoneal cytokine levels were significantly higher in patients with biliary fistulas as compared to those without biliary fistulas.Conclusions The peritoneal cytokine level is a sensitive parameter of peritoneal inflammation and can be as an additional diagnostic tool for the early prediction of biliary fistulas after biliary surgery.
