ADR Case Reports in Our Hospital During Nov. 2007～Oct. 2008: An Analysis of 246 Cases

VernacularTitle:我院2007年11月～2008年10月246例药品不良反应报告分析
Author: Zhenbo JIN ; Jie ZHUANG ; Jian HAN
Publication Type:Journal Article
Keywords: ADR; Report; Analysis; Rational use of drug
From: China Pharmacy 1991;0(06):-
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To study the situation and the related factors of ADR occurred in our hospital and to provide references for rational use of drug. METHODS: A total of 246 ADR case reports collected in our hospital from Nov. 2007 to Oct. 2008 were analyzed statistically. RESULTS: Of the 246 ADR cases, 120 kinds of drugs were involved. 64.63% of ADR were induced by intravenous drip infusion; 42.28% were antimicrobial,13.01% were drugs for central nervous system, 10.57% were for circulation system, 7.32% were TCM preparation; ADR-inducing TCM injection accounted for 50.00% in TCM preparations. The main clinical manifestation represented as lesion of skin and its appendants (51.63%). 11 severe cases accounted for 4.47% and 1 new cases only 0.41%. CONCLUSION: ADR may be caused by many factors. The most attention should be paid to monitoring ADR in the clinic so as reduce or avoid occurrence of ADR.