Apoptosis of NB4 Cells Induced by Artesunate
- VernacularTitle:青蒿琥酯诱导NB4细胞凋亡机制的研究
- Author:
Lei WU
- Publication Type:Journal Article
- Keywords:
Artesunate;
NB4 cell;
Apoptosis;
Caspase-3;
Activity
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the mechanism that apoptosis of NB4 cells were induced by artesunate. METHODS: The apoptosis of NB4 cell induced by artesunate was determined by Annexin V-FITC FCM analysis and cytomorphology and the activity of Caspase-3 was determined by ELISA assay. RESULTS: Artesunate could induce apoptosis of NB4 cell with the activity of Caspase-3 increasing. CONCLUSIONS: The apoptosis of NB4 cell induced by artesunate is achieved by activating Caspase-3.
