Efficacy Observation of Reduced Glutathione in the Treatment of Chemotherapeutics-induced Liver Lesion Caused by Chemotherapy in Cancer Patients
- VernacularTitle:还原型谷胱甘肽治疗化疗药物性肝损害的疗效观察
- Author:
Chunfang PENG
- Publication Type:Journal Article
- Keywords:
Reduced glutathione;
Chemotherapeutics;
Liver lesion
- From:
China Pharmacy
2007;0(28):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To observe clinical efficacy of reduced glutathione in the treatment of chemotherapeutics-induced liver lesion in cancer patients.METHODS:85 patients with drug-induced liver lesion after chemotherapy were randomly divided into 2 groups.Treatment group were treated with reduced glutathione and diammonium glycyrrhizinate injection (n=43) and control group were treated with diammonium glycyrrhizinate (n=42).Clinical efficacies of 2 groups were compared.RESULTS:After 2 weeks,average value of several index in treatment group were lower than in control group,there were significant difference between 2 groups (P
