Determination of Imperatorin in Jiedu Tongqiao Pills by HPLC
- VernacularTitle:HPLC法测定解毒通窍丸中欧前胡素的含量
- Author:
Ke CHEN
;
Ming KUANG
;
Rong YI
;
Ju CHEN
- Publication Type:Journal Article
- Keywords:
Jeidu tongqiao pills;
Imperatirin;
HPLC;
Content determination
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To determine imperatorin as the active ingredient of Angelica dahuricae in Jiedu tongqiao pills by HPLC. METHODS: The separation was performed on Waters Symmetryshielb33 C18(250 mm?4.6 mm,5 ?m) column with detection wavelength of 248 nm. The mobile phase consisted of methanol-water (65 ∶ 35) with flow rate of 1.0 mL?min-1.RESULTS:The linear range of imperatirin were 0.15～1.35 ?g. The average recovery was 100.4%(RSD=1.89%,n=9).CONCLUSION: The method is simple, accurate and reproducible for quality control of Jiedu tongqiao pills.
