Clinical Observation on Yangyin Shengxue Mixture in Prevention and Treatment of Radiation Injury of Oral Mucosa in Nasopharyngeal Carcinoma Patients:A Report of 30 Cases
- VernacularTitle:养阴生血合剂防治鼻咽癌患者放射性口腔黏膜损伤30例临床观察
- Author:
Yuezhen WANG
;
Wei FENG
;
Zhun WANG
;
Xia ZHOU
;
Xiao ZHENG
- Publication Type:Journal Article
- Keywords:
Radiation injury of oral mucosa;
Nasopharyngeal carcinoma;
Prevention and treatment with TCM;
Yanyin Shengxue Mixture (Herbal decoction for nourishing yin and blood)
- From:
Journal of Traditional Chinese Medicine
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the preventive and therapeutic effect of Yangyin Shengxue Mixture (Herbal decoction for nourishing yin and blood) on radiation-induced oral mucosal injury.Methods Sixty nasopharyngeal carcinoma patients were randomized into two groups: treatment group (30 cases) receiving Yangyin Shengxue Mixture three days before till one week after radiotherapy, and control group (30 patients) using conventional Tinidazole Gargle for prevention of oral-mucositis. Before and after treatment, the body weight, hemoglobin and state of infection of patients were examined. The time of occurrence of symptoms, degree of acute radiation mucositis and degree of pain were observed to evaluate the damage of oral mucosa according to RTOG standard for radiation injury of oral mucosa and Numeric Rating Scales (NRS). Results There were different degrees of radiation mucositis in both groups during radiotherapy, but the time of occurrence in the treatment group was significantly later than that of the control group (P
