Composition of Pathogenic Bacteria and Drug Resistance in Biliary Tract Infection:Analysis of 235 Cases
- VernacularTitle:235例胆道感染病原菌组成及其耐药性分析
- Author:
Shuqun ZHOU
;
Dingqiu ZHOU
- Publication Type:Journal Article
- Keywords:
Biliary tract infection;
Bile;
Pathogenic bacteria;
Drug resistance
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the composition of pathogenic bacteria and drug resistance in biliary tract infection for clinicians' reference about rational application of antibiotics. METHODS:Bacteria culture and drug susceptibility analysis were performed for the bile samples of 235 cases. RESULTS:The detection rate of pathogenic bacteria in bile was 61.7%,with gram-negative bacilli representing 59.3%,gram-positive bacilli 38.9% and Candida mycoderma 1.8%. With regard to constituent ratios of the bacteria,leading the first 4 places were enterococci(37.7%),Escherichia coli(29.3%),Klebsiella(18.6%) and Pseudomonas aeruginosa(5.4%). The main gram-negative bacilli were sensitive to imipenem and amikacin; whereas Enterococci were sensitive to vancomycin,amphemycin,ampicillin,penicillin and high concentration of gentamicin. ESBLs-producing Escherichia coli and Klebsiella totaled 30 strains,and the ESBLs-producing rate was 37.5%. CONCLUSION:Bile bacteria culture and drug resistance analysis serve as reference for clinical rational use of antibiotics.
