Application of Antibacterial Drugs in Patients with Open Fracture in One Hospital
- VernacularTitle:某院开放性骨折患者抗菌药物应用分析
- Author:
Na QIN
- Publication Type:Journal Article
- Keywords:
Open fracture;
Antibacterial;
Analysis
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the status quo of used antibacterial drugs in patients with open fracture in order to provide reference for clinical medication. METHODS:1 498 cases of open fracture in 2007 were analyzed statistically in respect of categories of antibiotic,application frequency of bacteria,result of bacteria culture,drug combination,usage and dosage and administration time,etc. RESULTS:In infection cases,patients were generally infected by Gram-negative bacteria and conducted drug combination for treatment and single drug for prevention. But some problems still occurred such as prophylactic use of antibiotics with high level,unreasonable drug combination,excessive dosage and long administration duration,etc. CONCLUSION:The ratio of antibacterial used in patients with open fracture reached up to 99.20%. The categories of used antibiotic were mainly ?-lactam,aminoglycosides and nitroimidazoles. There are many problems in the use of antibiotics in patients with open fracture,which should be standardized in administration.
