Chemical Stability of Disposable Infusion Bag of Total Parenteral Nutrition
- VernacularTitle:一次性使用静脉营养输液袋化学稳定性考察
- Author:
Xi WEI
- Publication Type:Journal Article
- Keywords:
Disposable infusion bag of total parenteral nutrition;
Chemical stability;
0.9% sodium chloride injection;
Cyclohexanone
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the chemical stability of disposable infusion bag of total parenteral nutrition.METHODS:0.9% sodium chloride injection was infused into the disposable infusion bag of total parenteral nutrition and set at 8 ℃ or 37 ℃ for different duration(0,24,48,and 72 h) as sample solution.The sample solution was compared with blank control(0.9% sodium chloride injection contained in glass bottle) in respect of pH value,metal ion,indissoluble particle,chloride,reduction substance,UV absorbance and dissolution of cyclohexanone.RESULTS:Each index was stable when sample solution was set at 8 ℃ for 24 h.Reduction substance and dissolution of cyclohexanone increased when solution was set at 37 ℃ with time prolonged,as compared with blank control.At 37℃ UV absorbance is more than that at 8 ℃.CONCLUSION:It is suitable to set disposable infusion bag of total parenteral nutrition at 8 ℃ after infusing with injection and use up within 24 h.
