Clinical Efficacy of Atorvastatin for Patients with Cerebral Infarction Complicating Carotid Atherosclerotic Plaque
- VernacularTitle:阿托伐他汀治疗脑梗死合并颈动脉粥样硬化斑块的临床研究
- Author:
Suhua WANG
;
Jiafan SUN
- Publication Type:Journal Article
- Keywords:
Atorvastatin;
Cerebral infarction;
Carotid atherosclerotic plaque;
Blood lipid;
C-reactive protein
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the therapeutic efficacy of atorvastatin for patients with carotid atherosclerotic plaques complicating cerebral infarction and the possible mechanism.METHODS:A total of 150 patients with cerebral infarction coexisting carotid atherosclerotic plaques were randomized to either control group (routine therapy against platelet aggregation) or trial group (routine therapy against platelet aggregation plus atorvastatin 20 mg?d-1).The scores of carotid atherosclerotic plaques,levels of blood lipid and C-reactive proteins (CRP) were compared between the two groups.RESULTS:At 6 and 12 months of follow-up,the scores of carotid atherosclerotic plaques in the trial group were significantly less than in the control group(P
