Correlation Between Consumption Amount of Commonly Used Antimicrobial Agents and Antibiotic Resistance Rate of Pseudomonas Aeruginosa
- VernacularTitle:铜绿假单胞菌耐药率与常用抗菌药物用量的相关性分析
- Author:
Haiying ZHANG
;
Yi FANG
;
Yuzhen LI
- Publication Type:Journal Article
- Keywords:
Antimicrobial agent;
Pseudomonas aeruginosa;
Resistance rate;
DDDs
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the correlation between the consumption amount of antimicrobial agents and antibiotic resistance rate of Pseudomonas aeruginosa(PA) in our hospital for clinical reference of rational use of antimicrobial agents.METHODS:The antibiotic resistance rate of PA and the consumption amount of anti-PA antimicrobial agents in our hospital from 2001 to 2007 were retrospectively analyzed.The correlation between the two was statistical analyzed by using SPSS12.0.RESULTS:The antibiotic resistance rate of PA increased year by year.However,the DDDs of the antimicrobial agents assumed diversified change.The antibiotic resistance rate of PA was positively correlated with the consumption amount of piperacillin/tazobactam(TZP),meropenem(MPM),ciprofloxacin(CIP) and moxifloxacin(MOX).CONCLUSION:The antibiotic resistance rate of PA showed an increasing trend in our hospital and which was positively correlated with the consumption sum of multi-kind of antimicrobial agents.
