The expression and significance of chemokine receptor CXCR4 in gastric carcinoma
- VernacularTitle:趋化因子受体CXCR4在胃癌中的表达及其意义
- Author:
Zhenglin WANG
;
Xiang HU
;
Pin LIANG
- Publication Type:Journal Article
- Keywords:
Stomach Neoplasms/pathol;
Receptors,Chemokines;
CXCR4;
Imunohistochemistry;
RT-PCR
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expresion and significance of CXCR4 in gastric cancer(GC) and intra-abdominal metastasis.Methods Immunohistochemistry and PT-PCR were used to detecte the expresion of CXCR4 protein and CXCR4 mRNA in GC,lynph node metastasis(LNM),peritoneal metastasis(PM) and normal stomach(NM) tissues.Results There was no CXCR4 expression in normal gastric mucosa cell.The expression rate of CXCR4 in GC and PM was 59.4%,100% respectively(P
