Central Randomization-based Modeling for Drug Allocation
- VernacularTitle:基于中央随机化的药物配送建模方法研究
- Author:
Fang CAO
- Publication Type:Journal Article
- Keywords:
Central randomization;
Mathematical model;
Drug allocation
- From:
China Pharmacy
2007;0(34):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To explore a randomization-based method for calculation of the required drug amount dynamically allocated by central drugstore of each clinical trial site. METHODS: Using the method of mathematical modeling with multiple related factors considered,everyday stock and drug demand of each trial site were calculated,and the model for drug-allocation was built. RESULTS: Calculating daily drug amount based on a real accomplished clinical trial. The validation on the established mathematical model showed that the simulated results met our primary goals. CONCLUSION: Management of central drugstore is an essential link of central randomization system. Reasonable calculation of drug amount allocated to each center with the use of mathematical modeling enhances the level of scientific management of central drugstores and ensures the smooth proceeding of clinical trials.
