Anti-tumor and Immunologic Enhancement Effects of Xiangling Capsule
- VernacularTitle:香苓胶囊抗肿瘤及增强免疫的作用研究
- Author:
Yan WANG
;
Yue LI
- Publication Type:Journal Article
- Keywords:
Xiangling capsule;
Cyclophosphamide(CTX);
Anti-tumor;
Immunologic enhancement;
Mice
- From:
China Pharmacy
2007;0(33):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To explore the anti-tumor and immunologic enhancement effects of Xiangling capsule.METHODS: The tumor-inhibition experiment was conducted in vivo in accordance with the screening criteria of anti-tumor drugs.Mice were treated with cyclophosphamide to induce hypoimmunity model.The effect of Xiangling capsule on mice was tested by determining leukocyte count,thymus index,spleen index,and the activity of NK cells.RESULTS: Xiangling capsules at different concentration showed inhibition on the growth of mice-transplanted tumor S180,H22 hepatomas and Lewis lung carcinoma with inhibition rates of 44.8%,52.2 %,and 43.3%,respectively(P