HPLC Fingerprints of Freeze-dried Xueshuantong for Injection
- VernacularTitle:注射用血栓通(冻干)的HPLC指纹图谱研究
- Author:
Dongjie LIN
- Publication Type:Journal Article
- Keywords:
Freeze-dried Xueshuantong for injection;
Fingerprint;
HPLC
- From:
China Pharmacy
2007;0(33):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish the HPLC fingerprints of the freeze-dried Xueshuantong for injection.METHODS: The HPLC chromatographic column was Zorbax SB-Aq-C18(250 mm?4.6 mm,5 ?m) and the mobile phase consisted of acetonitrile-water for gradient elution.The UV detection wavelength was set at 203 nm.RESULTS: There were 13 mutual peaks in the HPLC fingerprints of the freeze-dried Xueshuantong for injection.The relative retention time and relative peak area ratio of the fingerprints in which ginsenosides Rg1 served as internal standard were obtained.The area of non-mutual peaks represented no more than 5% of total peak area.CONCLUSION: The method is simple and reliable and it is applicable for the quality control of the freeze-dried Xueshuantong for injection.
