Anticoagulation Efficacy of Warfarin:Analysis of 95 Cases
- VernacularTitle:95例患者华法林抗凝情况分析
- Author:
Ce ZHENG
- Publication Type:Journal Article
- Keywords:
Warfarin;
Anticoagulation;
International normalized ratio
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To probe into the reasons behind the overanticoagulation and underanticoagulation in patients receiving warfarin.METHODS:95 patients hospitalized in our hospital from Jan.to Sept.in 2008 were analyzed in respect of patients' age,gender,weight,dosage of warfarin,international normalized ratio(INR),anticoagulation state,drug combination,etc.RESULTS:Patients' age and weight were correlated to the dosage and anticoagulative effect of warfarin,Levofloxacin was the most potent in enhancing the anticoagulative effect of warfarin.Of the 480 times of INR monitoring,the INR of 332 (69.2%) were within 2.0～3.0,and bleeding was noted in 7 cases (7.4%).CONCLUSION:The anticoagulative effect of warfarin is associated with many factors;therefore,it is urgent to tighten anticoagulative monitoring.
