Literature Analysis of Adverse Drug Reactions Induced by Mannitol
- VernacularTitle:甘露醇致不良反应文献分析
- Author:
Na SU
- Publication Type:Journal Article
- Keywords:
Mannitol;
Adverse drug reaction;
Literature analysis
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the general pattern and characteristics of the adverse drug reactions (ADR) induced by mannitol.METHODS:The literature related to the ADR induced by mannitol reported during 1999~2008 retrieved from CNKI was analyzed statistically.RESULTS:A total of 135 mannitol-induced ADR cases were collected,of which,males showed higher proportion than females,and the ADRs chiefly manifested as acute renal failure(30 cases,22.22%),followed by allergic reactions(17 cases,12.59%) and shock(17 cases,12.59%).CONCLUSION:Clinicians should tighten monitoring on the use of mannitol to reduce the occurrence of mannitol-induced ADR.