Determination of the Dissolution of Puerarin and 2,3,5,4'-tetrahydroxy-stibene-2-O-?-D-glycoside in Xinnaokang Capsules
- VernacularTitle:心脑康胶囊中葛根素和二苯乙烯苷的溶出度测定
- Author:
Qing YANG
;
Ying CHEN
- Publication Type:Journal Article
- Keywords:
Xinnaokang capsule;
Puerarin;
2,3,5,4'-tetrahydroxy-stibene-2-O-?-D-glycoside;
Dissolution;
HPLC;
Basket-rolling method
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine the dissolution of puerarin and 2,3,5,4'-tetrahydroxy-stibene-2-O-?-D-glycoside in Xinnaokang capsules.METHODS:The contents of puerarin and 2,3,5,4'-tetrahydroxy-stibene-2-O-?-D-glycoside were determined by HPLC and the dissolution rates of puerarin and 2,3,5,4'-tetrahydroxy-stibene-2-O-?-D-glycoside in Xinnaokang capsules were determined by basket-rolling method.RESUTLS:With water as releasing media,at a rotation rate of 100 r?min-1,the dissolution rate at 45 min was above 75% of the labeled amount.CONCLUSION:The method can be used for evaluation and control of the internal quality of Xinnaokang capsules.
