Curative Efficacy of Methylprednisolone Combined with Doxofyllin for Bronchial Asthma
- VernacularTitle:甲泼尼龙联合多索茶碱治疗支气管哮喘急性发作的疗效观察
- Author:
Hui YANG
- Publication Type:Journal Article
- Keywords:
Methylprednisolone;
Doxofyllin;
Bronchial asthma
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the curative efficacy of methylprednisolone combined with doxofyllin for acute attack of bronchial asthma. METHODS: A total of 132 patients with bronchial asthma were randomly divided into treatment group and control group: 70 cases in the treatment group were assigned to receive methylprednisolone for 3 days plus doxofyllin for 10 days in addition to the routine comprehensive therapy,and 62 in the control group to receive dexamethasone for 3 day plus aristophyllin injection for 10 days in addition to the routine comprehensive therapy. RESULTS: The total effective rate and the total clinical control rate in the treatment group were signficantly higher than in the control group (92.9% vs. 77.4% in total effective rate,P=0.019;45.7% vs.27.4% in total clinical control rate,P=0.03). Compared with the control group,the treatment group showed marked improvment in lung function and blood gas analyses yet with fewer adverse drug reactions,all showing differences between the two groups (P
