Curative Efficacy of Letrozole Combined with Traditional Chinese Medicine for Ovulation Dysfunction Caused by Polycystic Ovarian Syndrome
- VernacularTitle:来曲唑配合中药治疗多囊卵巢综合征排卵障碍的疗效观察
- Author:
Xiaoqiao AN
;
Guijuan LIU
;
Jingyu ZHANG
;
Fujin CAI
;
Xintao AN
;
Shoufeng JIAO
- Publication Type:Journal Article
- Keywords:
Letrozole;
Traditional Chinese medicine;
Polycystic ovarian syndrome;
Ovulation dysfunction;
Curative efficacy
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the clinical efficacy and safety of letrozole combined with traditional Chinese medicine for ovulation dysfunction induced by polycystic ovarian syndrome(PCOS). METHODS: 300 PCOS outpatients were randomized to 3 groups of 100 each: clomiphene citrate (CC) group (188 cycles);urinary gonadotropin (HMG) group (104 cycles) and letrozole (LE) group (155 cycles). The occurrence rate of mature follicle,ovulation rate,pregnancy rate,abortion rate,superfoetation-terata rate,cancellation rate,incidence of no dominant follicle forming and OHSS etc were compared between the two groups after treatment. RESULTS: 30 babies were born in CC group,34 in HMG group and 43 in LE group were born. The occurrence rate of mature follicles,ovulation rate and pregnancy rate in the LE group were higher than in either CC group or HMG group(P0.05);the superfoetation rate in HMG group was higher than in CC group or LE group(P
