ADR Caused by Quinolones:Analysis of 199 Cases in Our Hospital
- VernacularTitle:我院199例喹诺酮类药不良反应报告分析
- Author:
Jie GAO
;
Cheng XIE
;
Liyan MIAO
- Publication Type:Journal Article
- Keywords:
Quinolones;
Adverse drug reaction;
Analysis of case report
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the characteristics of adverse drug reactions (ADR) caused by quinolones in our hospital and to promote their rational use in clinic. METHODS: By a retrospective review,a total of 199 quinolones-induced ADR cases collected from May 2004 to December 2007 in our hospital were analyzed statistically in respect of patients' gender and age,drug species involved,past ADR history,route of administration,clinic manifestations,etc. RESULTS: A total of 9 kinds of quinolones involved in the 199 ADR cases,of which,118 cases were induced by levofloxacin,16.1% had past ADR history,93.5% of the ADR cases were induced via intravenous drip,and most common presentations of the ADR were lesions of skin and its appendants as well as digestive system. There were 7 serious ADR cases. CONCLUSION: The indications of quinolones should be controlled strictly,which should be preferably administered orally and monitoring of its administration should be emphasized in clinical practice to decrease and avoid the occurrence of ADR.
