Montmorillonite Powder Combined with Vitamin B_6 for Azithromycin-induced Adverse Reactions of Gastrointestinal Tract:Clinical Randomized Control Trials
- VernacularTitle:蒙脱石散与维生素B_6联合应用减轻阿奇霉素胃肠道不良反应的临床随机对照研究
- Author:
Shuhui XU
- Publication Type:Journal Article
- Keywords:
Azithromycin;
Montmorillonite powder;
Vitamin B6;
Adverse reactions of gastrointestinal tract
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy of combined use of montmorillonite powder and vitamin B6 to attenuate azithromycin-induced adverse reactions of gastrointestinal tract. METHODS: 103 patients with respiratory infection in the outpatient pediactric department treated with azithromycin were enrolled: 53 cases (treatment group) received montmorillonite powder plus vitamin B6 additionally,and 50 cases(control group) were not given montmorillonite powder and vitamin B6. RESULTS: The incidence of adverse reaction of gastrointestinal tract was 15.1% for treatment group versus 48.0% for control group,showing significant differences between the two groups(?2=95.025,P
