Correlation Between Antibiotic Resistance and Consumption of Antimicrobials and Countermeasures for Clinical Treatment
- VernacularTitle:细菌耐药率与抗菌药物用量相关性分析及临床治疗对策
- Author:
Yan LU
- Publication Type:Journal Article
- Keywords:
Antibiotics;
Medication frequency;
Drug resistance rate;
Countermeasures for clinical treatment
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the consumption of antibiotics and the trend of antibiotic resistance rate in our hospital for clinical reference of rational application of antibiotics. METHODS:The consumption of antibiotics in our hospital from 2007 to 2008 was investigated by DDDs analytical method,and the synchronous isolation results of the pathogens and the resistance rates of pathogens to different kinds of antibiotics were analyzed comparatively to search a countermeasure for clinical treatment with antibiotics. RESULTS: In terms of DDDs,leading the list was ?-lactam,followed by macrolides. The infection in our hospital was mostly induced by Escherichia Coli,followed by Pseudomonas aeruginosa and Staphylococcus aureus. The resistance rates of pathogens to penicillins and macrolide antibiotics were the highest. Drug resistance rate was correlated to consumption of antibiotics. CONCLUSION: Anti-infective treatment should be carried out based on the drug susceptibility test;the use of antibiotics should be used rationally according to their clinical efficacy,and the consumption of antibiotics should be controlled to prevent or delay the production of antibiotic resistance.
