Effect of panax notoginseng saponins on electrophysiological characteristic of atrial cardiomyocytes in guinea pig
- VernacularTitle:三七总皂甙对豚鼠心房肌细胞电生理特性的影响
- Author:
Ying YANG
;
Yongqing TANG
;
Yihan CHEN
- Publication Type:Journal Article
- Keywords:
Panax notoginseng saponins;
Atrial cardiomyocyte;
Action potentials;
Guinea pig
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To study the effect of panax notoginseng saponins on the left atrial appendage(LAA)of the guinea pigs.METHODS:Standard microelectrode intracellular recording technique was used to record the LAA action potential(AP)and the effective refractory period(ERP)in the guinea pigs during the pouring with different density of PNS.RESULTS:The effect of PNS in concentration of 0.7,7,70,700 mg/L was significant at 20 min,the APD50 and APD80 of the pouring at 20 min,30 min,40 min of the 70 mg/L was longer than the reference group(P
