Apoptosis in sepsis
- VernacularTitle:脓毒症中的细胞凋亡
- Author:
Yan ZHANG
;
Xucheng JIANG
;
Xiaokui GUO
- Publication Type:Journal Article
- Keywords:
Sepsis;
Apoptosis;
Cytokines
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Immune cells that undergo increased apoptosis include lymphocytes and macrophages,yet the apoptosis of neutrophils is decreased in sepsis.Increase in apoptosis has also been reported in non-immune cells such as gastrointestinal cells,epithelial cells of lung as well as endothelial cells.The altered apoptotic cell death may contribute to the initiation and aggravation of immune and organ dysfunction in sepsis.Elucidating the changes and mechanism of apoptosis and taking measures to control apoptosis may be an effective strategy for the treatment of sepsis.
