Efficacy of Allicin for Restenosis of Geriatric Myocardial Infarction after Percutaneous Coronary Intervention
- VernacularTitle:蒜素对老年心肌梗死患者经皮冠状动脉介入术后再狭窄的临床疗效观察
- Author:
Kai WANG
- Publication Type:Journal Article
- Keywords:
Allicin;
Geriatric myocardial infarction;
Restenosis after percutaneous coronary intervention(PCI)
- From:
China Pharmacy
2007;0(27):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the adjunctive efficacy of allicin for restenosis of geriatric myocardial infarction (MI) after percutaneous coronary intervention (PCI). METHODS:From Jan.to Dec.2007,150 geriatric MI patients after PCI were divided into 2 groups (n=75 each),i.e. conventional therapy group and allicin group (allicin 40 mg tid plus conventional therapy). After treatment for 1 year,plasma levels of restenosis markers including endothelin-1,CRP,NO were tested; Coronary arteriography was carried out to reveal the restenosis situation; Angina attack frequencies were also recorded. RESULTS:66 cases in allicin group vs.57 in conventional therapy group had no recurrence of angina,with the effective rate being 88% in allicin group vs.76% in conventional therapy group,showing significant differences between the two groups (P
