Efficacy of Reduced Glutathioue plus Xiangdan Injection for Anti-Tuberculosis Drug-induced Hepatic Lesion
- VernacularTitle:还原型谷胱甘肽联合香丹注射液治疗抗结核药所致肝损害疗效观察
- Author:
Jiahui NING
;
Dalang HUO
- Publication Type:Journal Article
- Keywords:
Reduced glutathioue;
Xiangdan injection;
Pulmonary tuberculosis;
Hepatic lesion
- From:
China Pharmacy
2007;0(27):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the therapeutic efficacy of reduced glutathioue plus Xiangdan injection for anti-tuberculosis drug-induced hepatic lesion. METHODS:A total of 75 patients with anti-tuberculosis drug-induced hepatic lesion were randomly divided into two groups:38 cases (trial group) were assigned to receive reduced glutathioue (1.2 g) that was added into normal saline(250 mL) by iv gtt q.d plus Xiangdan injection (20 mL) that was added into 10% glucose injection (250 mL) q.d by iv gtt;37 cases(control group)received potassium magnesium injection (20 mL)which was added into 10% glucose injection(250 mL) q.d by iv gtt. After treatment for 4 weeks,the liver function parameters and the total effective rates in two groups were measured. RESULTS:Compared with control group,the liver function had a significantly better improvement in trial group (P
